correlation of fitness effects estimated from different sequence sets

The scatter plots show the correlation of amino-acid fitness effects estimated using different sets of sequences.

The line and orange text show the Pearson correlation.

Mouse over points for details on specific mutations.

The minimum expected count slider below the plot indicates how many expected counts of an an amino acid we require before making a fitness estimate. Larger values yield more accurate estimates but for fewer amino acids. So move the slider to the left to show estimates for more amino acids at lower confidence, and move it to the right to show estimates for fewer amino acids at higher confidence.

See Bloom and Neher (2023) for a paper describing the work.

See https://github.com/jbloomlab/SARS2-mut-fitness for full computer code and data.

See https://jbloomlab.github.io/SARS2-mut-fitness/ for links to all interactive plots.

This plot is for the public_2023-06-21 dataset. Here are all plots for that dataset.